The Center for Environmental Genetics (CEG) was established in 1992 and is funded by the National Institute for Environmental Health Sciences (NIEHS) to study how gene-environment interactions, via epigenetics, contribute to the developmental origins of health and disease. The Center has been led since 2007 by Shuk-Mei Ho, PhD, Jacob G. Schmidlapp Professor & Chair of Environmental Health and Director of the Cincinnati Cancer Center. As one of only a select number of such centers nationwide, the CEG is helping to increase the amount and quality of environmental health sciences research, attract new investigators to the field, educate and train the next generation of leaders, and enhance research infrastructure at both the University of Cincinnati and Cincinnati Children’s Hospital. Core activities of the CEG include its
- Pilots Projects Program (PPP) which awards seed-money to promising researchers whose work has the potential to exert a meaningful impact on environmental science, genetic research, andhuman health.
- Career Development Program (CDP), which provides new and aspiring researchers with expert mentoring and diverse professional development opportunities.
- Integrative Health Sciences Facilities (IHS) Core, which offers expert consultation and services in study design, exposure assessment, data collection and analysis. The IHS core also assists in collecting, processing, and storing biospecimens; maintains a database of laboratories available to analyze these analytes (MEB-Labs Database); and conducts workshops on how to select and process biomarkers of exposure.
- Integrative Technologies Support (ITS) Core: Offers expert consultation and laboratory services in genomics/epigenomics, genotyping, proteomics, metallomics, metabolomics and exposure and functional imaging.
- Bioinformatics Core: Offers state-of-the-art support for genomic data management/ data analysis, experimental design, mechanistic interpretations through integrative systems biology analysis, access to public domain data, databases, structural bioinformatics, etc.
- Community Outreach and Engagement Core (COEC): Serves to translate advanced environmental health science for our constituents, including public health decision-makers, community-based health care professionals, and vulnerable populations, in particular minority and underserved neighbors. COEC also facilitates mutually instructive partnerships among researchers and clinicians, public health agencies, and affected community populations.