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Looking Upstream for Environmental Links to Breast Cancer

About Our Speakers

Ann Hernick
President, Breast Cancer Alliance of Greater Cincinnati

An active advocate with the Cincinnati BCERC since it was proposed in 2003, Ms. Hernick is a Co - Investigator with Growing Up Female and the COTC. She is Chair of the Center's COTC Education Committee, which plans the annual Looking Upstream public forum. A breast cancer survivor, she is a past and current president of the Breast Cancer Alliance of Greater Cincinnati, and serves on the Board of Directors of the National Breast Cancer Coalition (NBCC). She is a 2006 graduate of the NBCC science training program called Project LEAD. Recently, Ms. Hernick has been selected to serve as a peer-reviewer for the Department of Defense Breast Cancer Research Program and as a participant in the 2010 Research Advocate Network, Focus on Research. She is a frequent speaker locally, regionally and nationally on advocates' role in the BCERC research and dissemination of results.


Kenneth Setchell, PhD

Professor, Division of Pathology & Laboratory Medicine, Cincinnati Children’s Hospital Medical Center and Department of Pediatrics, University of Cincinnati

Dr. Setchell cites more than 200 scientific publications and has presented over 250 papers at national and international symposia, while serving on national and international committees and editorial boards. Dr. Setchell was awarded the 1997 Gilbride award by the Canadian Liver Foundation for his contributions to the diagnosis and treatment of liver disease. In 1999 at the AOCS 3rd International Symposium on the "Role of Soy in Preventing and Treating Chronic Disease" he was recognized for his outstanding contributions to increasing our understanding and awareness of the health benefits of soy foods and soybean constituents. In 2000 he received the annual award from the North American Menopause Society (NAMS) for his research on soy and women's health. He received the Roche 2003 International Award for Innovative Research in Human Nutrition for his discoveries of classes of phytoestrogens and the 2004 Adolf Windaus Prize for research on bile acids and the discovery of genetic defects in the cholesterol-bile acid pathway causing liver disease.


Glendon Zinser, PhD

Assistant Professor, Department of Cancer and Cell Biology, University of Cincinnati

Dr. Zinser studies the influence that nutritional modifications have on glandular development, thus modulating tissue susceptibility to cancer in response to environmental factors. Focusing on Vitamin D3, his laboratory investigates 1) the ability of breast adipocytes to contribute to the vitamin D-induced growth inhibition of breast epithelial cells; 2) the impact of elevated serum levels of vitamin D on pubertal mammary gland development and carcinogen induced tumorigenesis; 3) the epigenetic changes that likely result due to elevated serum Vitamin D levels, offering long term protection against mammary tumorigenesis; and 4) the importance of VDR signaling within the adipose tissue. These investigations involve the use of various cellular and molecular procedures including cell culture, three-dimensional co-culture systems, primary cell isolation and in vivo studies using knockout and transgenic mice.


Mary Justice, RN, MSN

Associate Professor of Nursing, Raymond Walters College, University of Cincinnati

Ms. Justice is an active and committed member of the breast cancer advocacy community in Greater Cincinnati. A breast cancer survivor, she serves on the Cincinnati BCERC COTC Committee which plans the annual Looking Upstream public forum and other outreach efforts. She is a member of the Oncology Nursing Society and has served as a consumer reviewer of the US Department of Defense Breast Cancer Research Program. She is a past member of the Breast Cancer Alliance of Greater Cincinnati Board of Directors.


Frank Biro, MD

Professor, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

Dr. Biro is the Director of Adolescent Medicine at Cincinnati Children’s and an expert in the field of puberty. Dr. Biro graduated from Harvard Medical School and completed a combined residency in Internal Medicine and Pediatrics at the University of Rochester. He returned to Harvard for a fellowship in Adolescent Medicine, and subsequently joined the staff of Cincinnati Children’s in 1984. Dr. Biro is immediate past president of the North American Society for Pediatric and Adolescent Gynecology (NASPAG), and is a member of the Editorial Advisory Board of the Journal of Pediatric and Adolescent Gynecology. His research interests include the antecedents of pubertal maturation and the impact of pubertal development on adult morbidity and mortality. He is principal investigator of the Growing Up Female epidemiologic study of the Cincinnati Breast Cancer & the Environment Research Center (BCERC).


Jennifer Ruschman, ScM, CGC

Clinical Manager, Cincinnati Children’s Hospital Medical Center

Ms. Ruschman is currrently the clinical manager for the Division of Human Genetics at Cincinnati Children’s Hospital Medical Center. Her clinical expertise is in cancer genetics and genetic laboratory services, and she has provided clinical genetic counseling services for over eight years. She has coordinated numerous educational activities for lay persons and health care professionals as part of this program since 2002. She is a member of the National Society of Genetic Counselors, and is a founding member of the Ohio Department of Health Cancer Genetics Workgroup. She currently serves as a co-investigator for the Community Outreach and Translation Core of the Cincinnati Breast Cancer and the Environment Research Center (BCERC). Ms. Ruschman will be joining the Business Development team at Cincinnati Children's focusing on expanding CCHMC's world renowned healthcare programs and improving child health.


M. Kathryn Brown, PhD
Assistant Professor, Department of Environmental Health, University of Cincinnati

Dr. Brown is Director of the Community Outreach and Translation Core (COTC) of the Cincinnati Breast Cancer and the Environment Research Center (BCERC). There she works with breast cancer advocates to conduct educational programs that address both the current knowledge and recent study findings of the impact of environmental exposures on puberty and breast cancer. Dr. Brown’s background includes population-based studies of childhood lead exposures in urban neighborhoods and in western Superfund sites; working with African-American and urban Appalachian neighborhoods on environmental justice issues; establishing imby -in my backyard- a community health and environment research center; and service on advisory boards including the US EPA National Environmental Justice Advisory Council. She received her masters and doctoral degrees in Environmental Epidemiology from the University of Cincinnati.


Marshall Anderson, PhD

Professor, Department of Cancer and Cell Biology, University of Cincinnati

Dr. Anderson’s 40 year scientific career has included leadership positions in molecular toxicology for the National Institute of Environmental Health Sciences (NIEHS), and more recently the directorship of the Department of Environmental Health at the University of Cincinnati, before joining the Department of Genome Science in 2004. He was named Deputy Director of the Cincinnati BCERC in 2006. His research interests include the role of oncogenes and tumor suppressor genes in tumor development (esp. in lung cancer), the mechanisms by which toxic chemicals cause cancer and the impact of genetic diversity on the response of the individual to toxic environmental agents. Dr. Anderson leads the Genetic Epidemiology of Lung Cancer Consortium of 11 research sites nationally, which in 2004 discovered evidence of lung cancer susceptibility genes in humans. He is Deputy Director of the Cincinnati BCERC.


Susan Pinney, PhD

Associate Professor, Department of Cancer and Cell Biology, University of Cincinnati

Dr. Pinney’s primary area of research is in cancer epidemiology, both genetic susceptibility and traditional incidence and prevalence studies. She is the environmental epidemiologist for the “Environmental Factors in Female Development and Disease” study of the NCI/NIEHS funded Breast Cancer and the Environment Research Center at UC and Cincinnati Children’s Hospital Medical Center, and Director of the Breast Cancer Registry of Greater Cincinnati. She also is a member of the Genetic Epidemiology of Lung Cancer Consortium, a nationwide study of gene-environment interaction of cigarette smoking and lung cancer. Dr. Pinney’s other research also includes studies of cancer incidence in community populations and workers exposed to ionizing radiation, nephrotoxicity in populations exposed to uranium, and health effects in populations exposed to perfluoroalkyl compounds.
 

 

April 24, 2010 Forum

 
Key Points of Forum Presentations
 

Speakers

Ann Hernick
Welcome and Introductions
PowerPoint Presentation
 
Kenneth Setchell, PhD
Soy and Breast Cancer
Handout
 
Glendon Zinser, PhD
Vitamin D and Breast Cancer
PowerPoint Presentation
Handout
 
Frank Biro, MD
Growing Up Female Study Update
PowerPoint Presentation
 
 

Poster Presentations

Poster Session Description
Measurement of Fat Mass: Concordance between Field Research Measures and Dual-Energy X-ray Absorptiometry
Erin R. Baker, Jane C. Khoury, Susan M. Pinney, Frank M. Biro, and Kim N. Dietrich
Poster Abstract
 
Translating BCERC Findings into Usable Information: Four Messages for Dissemination
Janice Barlow, Kami Silk, Ann Hernick and Donna Duncan
Poster Abstract
 
BCERC Collaborative Partnerships: Perspectives of a Breast Cancer Advocacy Organization
Ann D. Hernick and Kathleen M. Ball
Poster Abstract
 
Factors Influencing Retention and Participation of Girls in a Longitudinal Study
Anita R. Hurst, Amanda K. Kolb, Justin R. Bates and Frank M. Biro
Poster Abctract
 

Panel Discussion

Purpose of Panel Discussion
 
Jennifer Ruschman, Marshall Anderson, Frank Biro, M Kathryn Brown, Ann Hernick and Susan Pinney
PowerPoint Presentation