Aimin Chen

Assistant Professor

Division: Epidemiology

Phone: 513-558-2129
Location: 141 Kettering Lab
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Dr. Chen’s primary research interest is perinatal and pediatric epidemiology, studying environmental chemicals and reproductive and neurodevelopmental outcomes, preterm birth, and obesity. He has conducted epidemiologic research on DDT, isoflavones, lead, mercury, cadmium, and tobacco smoke. His past work includes: 1) risk and benefit analysis on DDT use for malaria control in sub-Saharan Africa; 2) effects of isoflavones (mainly genistein and daidzein) in soy infant formula; 3) heavy metal exposures and child IQ and behavior; 4) maternal smoking and child obesity; 5) maternal obesity, gestational weight gain, and infant death; 6) preterm birth subtypes and infant health. His recent research focuses are adverse pregnancy outcomes and neurodevelopment after exposures to electronic waste recycling and PBDEs in women of reproductive age and their children.

Related News:

  • 05/28/2014: Can Fire Retardants Raise Risk of Children Born With Lower IQs?
  • 09/04/2013: Environmental Health Faculty Students Enjoy Successful Conference in Basel Switzerland
  • 07/22/2013: E-Waste Recycling in China: A Health Disaster in the Making?
  • 07/01/2013: NIEHS spurs investigation into the health effects of e-waste recycling
  • 02/10/2012: Is cadmium the new lead?
  • 02/15/2011: University of Cincinnati to Study the Effects of E-Waste
  • 11/24/2010: Chinese UC researchers study e-waste
  • 01/11/2010: Toxic metal found in kids' jewelry very dangerous

  • Education

    1994 MD Preventive Medicine, Nanjing Medical University, Nanjing, China

    1997 MS Epidemiology, Nanjing Medical University, Nanjing, China

    2002 PhD Epidemiology and Health Statistics, Fudan University, Shanghai, China

    2002-2006 Postdoctoral Fellow, Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, N


    2002-2006 Visiting Fellow Award, National Institutes of Health

    2004 Trainee Research Recognition Award, Milk Club of the Society for Pediatric Research, Pediatric Academic Societies’ Meeting

    2006 Fellows Award for Research Excellence (FARE), NIH Fellows Committee, the Scientific Directors, the NIH Office of Research on Women’s Health, and the NIH Office of Intramural Training and Education

    2008 Excellent Reviewer (<10%) for Human Reproduction

    2011 Environmental Health Sciences Science Communication Fellowhip

    Professional Experience

    1997-1999 Public Health Physician, Jiangsu Province Center for Disease Control and Prevention, Nanjing, China

    2006-2009 Assistant Professor, Department of Preventive Medicine and Public Health, Creighton University School of Medicine, Omaha, NE

    2010- Assistant Professor, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH


    RC4 ES01975509/27/2010-09/30/2013. National Institute of Environmental Health Sciences. Human Developmental Toxicity of Metal Mixture Exposure from E-Waste Recycling, PI, Active.

    SRS 00751805/01/2011-11/30/2012. Passport Foundation. Prenatal Exposure to PDBEs and Child Neurobehavior at Three Years of Age, PI, Closed.

    R01ES02034908/23/2011-04/30/2016. National Institute of Environmental Health Sciences. Longitudinal Study of Exposure to PBDEs and PFCs and Child Neurobehavior, PI, Active.

    R21ES02110607/09/2012-06/30/2014. National Institute of Environmental Health Sciences. Multiple Risk Factors and Neurodevelopment Deficits in Rural Appalachian Children, Collaborator, Active.

    P30ES00609604/01/2013-03/31/2018. National Institute of Environmental Health Sciences. Environmental Genetics, Collaborator, Active.

    1R01ES02293309/04/2013-05/31/2017. National Institute of Environmental Health Sciences. Development Of A Lab-on-a-Chip For Point-of-Care Biomonitoring Of Blood Metals, Collaborator, Awarded.

    Selected Publications

    Chen A, Rogan WJ. Nonmalarial infant deaths and DDT use for malaria control. Emerging Infectious Diseases 2003; 9(8):960-4

    Chen A, Rogan WJ. Breastfeeding and the risk of postneonatal death in the United States. Pediatrics 2004;113(5):e435-9

    Chen A, Rogan WJ. Isoflavones in soy infant formula: a review of evidence for endocrine and other activity in infants. Annual Review of Nutrition 2004; 24:33-54

    Chen A, Yuan W, Meirik O, Wang X, Wu SZ, Zhou L, Luo L, Gao E, Cheng Y. Mifepristone-induced early abortion and outcome of subsequent wanted pregnancy. American Journal of Epidemiology 2004;160(2):110-7

    Chen A, Dietrich KN, Ware JH, Radcliffe J, Rogan WJ. IQ and blood lead from 2 to 7 years of age – are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environmental Health Perspectives 2005;113(5):597-601

    Rogan WJ, Chen A. Health risks and benefits of bis(4-chlorophenyl)-1,1,1- trichloroethane (DDT). Lancet 2005;366(9487):763-73

    Chen A, Zhang J, Zhou L, Gao E, Chen L, Rogan WJ, Wolff MS. DDT serum concentration and menstruation among young Chinese women. Environmental Research 2005;99(3):397-402

    Chen A, Pennell ML, Klebanoff MA, Rogan WJ, Longnecker MP. Maternal smoking during pregnancy in relation to child overweight: follow-up to age 8 years. International Journal of Epidemiology 2006;35(1):121-30

    Chen A, Schwarz D, Radcliffe J, Rogan WJ. Maternal IQ, Child IQ, behavior and achievement in urban 5-7 year olds. Pediatric Research 2006;59(3):471-7

    Chen A, Rhoads GG, Cai B, Salganik M, Rogan WJ. The effects on chelation on blood pressure in lead-exposed children: a randomized study. Environmental Health Perspectives 2006;114(4):579-83

    Chen A, Cai B, Dietrich KN, Radcliffe J, Rogan WJ. Lead exposure, IQ, and behavior in urban 5- to 7- year olds: Does lead affect behavior only by lowering IQ? Pediatrics 2007; 119(3):e650-658

    Chen A, Basso O. Does low maternal blood pressure during pregnancy increase the risk of perinatal death? Epidemiology 2007;18(5):619-622

    Chen A, Feresu SA, Fernandez C, Rogan WJ. Maternal obesity and the risk of infant death in the U.S. Epidemiology 2009;20(1):74-81

    Zhu QX, Gao ES, Chen A, Luo L, Cheng YM, Yuan W. Mifepristone-induced abortion and placental complications in subsequent pregnancy. Human Reproduction 2009; 24(2):315-319

    Chen A, Klebanoff MA, Basso O. Prepregnancy body mass index change between pregnancies and preterm birth in the following pregnancy. Paediatric and Perinatal Epidemiology 2009; 23(3):207-215

    Eskenazi B, Chevrier J, Rosas LG, Anderson HA, Bornman R, Bouwman H, Chen A, Cohn BA, de Jager C, Henshel DS, Leipzig F, Leipzig JS, Lorenz EC, Snedeker SM, Stapleton D. The Pine River Statement: Human Health Consequences of DDT Use. Environmental Health Perspectives 2009;117(9):1359-1367

    Chen A, Feresu SA, Barsoom MJ. Heterogeneity of preterm birth subtypes in relation to neonatal death. Obstetrics and Gynecology 2009;114(3):516-522

    Cao Y, Chen A, Radcliffe J, Dietrich KN, Jones RL, Caldwell KL, Rogan WJ. Postnatal cadmium exposure and neurodevelopment and blood pressure in Children 2, 5, and 7 years of age. Environmental Health Perspectives 2009;117(10):1580-1586

    Gonsalves WI, Cornish N, Moore M, Chen A, Varman M. Effects of volume and site of blood draw on blood culture results. Journal of Clinical Microbiology 2009; 47(11):3482-3485

    Pomajzl RJ, Varman M, Holst A, Chen A. Hemolytic uremic syndrome (HUS)–incidence and etiologies at a regional Children’s Hospital in 2001-2006. European Journal of Clinical Microbiology & Infectious Diseases 2009; 28(12):1431-1435

    Cao Y, Chen A, Jones RL, Radcliffe J, Dietrich KN, Caldwell KL, Rogan WJ. Does background methyl mercury exposure in toddlers affect IQ and neurodevelopment? Neurotoxicology 2010; 31(1):1-9

    Miao M, Gao E, Chen A, Luo L, Cheng Y, Yuan W. Mifepristone-induced abortion and duration of third stage labour in a subsequent pregnancy. Paediatric and Perinatal Epidemiology 2010; 24(2):125-130

    Guo Y, Huo X, Li Y, Wu K, Liu J, Huang J, Zheng G, Xiao Q, Yang H, Wang Y, Chen A, Xu X. Monitoring of lead, cadmium, chromium and nickel in placenta from an e-waste recycling town in China. Science of the Total Environment 2010; 408(16):3113-3117

    Ma J, Lu HY, Xia XK, Dong HB, Gu AH, Li ZY, Li Z, Chen A, Wang XR, Wang SL. BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population. Biology of Reproduction 2010;83(4):656-62

    Basso O, Pennell ML, Chen A, Longnecker MP. Mother’s age at menarche and offspring growth. International Journal of Obesity 2010;34(12)1766-1771

    Alla VM, Anand K, Hundal M, Chen A, Karnam S, Hee T, Hunter C, Mooss AN, Esterbrooks D, Mohiuddin SM. Impact of moderate to severe renal impairment on mortality and appropriate shocks in patients with implantable cardioverter defibrillators. Cardiology Research and Practice 2010; Article ID 150285, doi:10.4061/2010/150285

    Cao Y, Chen A, Jones RL, Radcliffe J, Dietrich KN, Caldwell KL, Peddada S, Rogan WJ. Efficacy of succimer chelation of mercury at background exposures in toddlers: randomised trial. Journal of Pediatrics 2010;158(3):480-485.e1

    Chen A, Dietrich KN, Huo X, Ho SM. Developmental neurotoxicants in e-waste: an emerging health concern. Environmental Health Perspectives 2011;119(4): 431-438

    Akhtar J, Irazuzta J, Chen A. Learner’s evaluation in paediatric intensive care unit. Emergency Medicine Journal 2011;28(9):758-760

    Liu J, Xu X, Wu K, Piao Z, Huang J, Guo Y, Li W, Zhang Y, Chen A, Huo X. Association between lead exposure from electronic waste recycling and child temperament alterations. Neurotoxicology 2011;32(4):458-464

    Chen A, Chung E, DeFranco EA, Pinney SM, Dietrich KN. Serum PBDEs and age at menarche in adolescent girls: analysis of the National Health and Nutrition Examination Survey 2003-3004. Environmental Research 2011;111(6):831-837

    Haynes EN, Chen A, Ryan PH, Succop PA, Wright J, Dietrich KN. Exposure to airborne metals and particulate matter and risk for youth adjudicated for criminal activity. Environmental Research 2011;111(8):1243-1248

    Liang H, Gao E, Chen A, Luo L, Cheng Y, Yuan W. Mifepristone-induced abortion and vaginal bleeding in subsequent pregnancy. Contraception 2011;84(6):609-614

    Loftin R, Chen A, Evans A, DeFranco EA. Racial differences in gestational age specific neonatal morbidity: further evidence for different gestational lengths. American Journal of Obstetrics & Gynecology 2012;206(3):259.e1-6

    Xu X, Yang H, Chen A, Zhou Y, Wu K, Liu J, Zhang Y, Huo X. Birth outcomes related to informal e-waste recycling in Guiyu, China. Reproductive Toxicology 2012;33(1):94-8

    Haynes EN, Ryan PH, Chen A, Brown D, Roda S, Kuhnell P, Wittberg D, Terrell M, Reponen T. Assessment of personal exposure to manganese in children living near a ferromanganese refinery. Science of the Total Environment 2012;427-428:19-25

    Kamath-Rayne BD, DeFranco EA, Chung E, Chen A. Subtypes of preterm birth and the risk of postneonatal death. Journal of Pediatrics 2013;162(1):28-34.e2

    Chen A, Kim SS, Chung E, Dietrich KN. Thyroid hormones in relation to lead, mercury, and cadmium exposure in the National Health and Nutrition Examination Survey, 2007–2008. Environmental Health Perspectives 2013;121(2):181-186

    Chen A, Park JS, Linderholm L, Rhee A, Petreas M, DeFranco EA, Dietrich KN, Ho SM. Hydroxylated polybrominated diphenyl ethers in paired maternal and cord sera. Environmental Science & Technology 2013;47(8):3902-3908

    Cao Y, Chen A, Bottai M, Caldwell KL, Rogan WJ. The impact of succimer chelation on blood cadmium in children with background exposures: A randomized trial. Journal of Pediatrics 2013;163(2):598-600

    Kim SS, Arora M, Fernandez C, Landero J, Caruso J, Chen A. Lead, mercury, and cadmium exposure and attention deficit hyperactivity disorder in children. Environmental Research 2013; 126:105-110 (PMCIC: PMC3847899)

    Wang Y, Chen A, Dietrich KN, Radcliffe J, Caldwell KL, Rogan WJ. Postnatal exposure to methyl mercury and neuropsychological development in 7-year-old urban inner-city children exposed to lead in the United States. Child Neuropsychology 2014;20(5):527-538

    Braun JM, Kalkbrenner AE, Just AC, Yolton K, Calafat AM, Sjödin, Hauser R, Webster GM, Chen A, Lanphear BP. Gestational exposure to endocrine disrupting chemicals and reciprocal social, repetitive, and stereotypic behaviors in 4 and 5 year old children. Environmental Health Perspectives 2014;122(5):513-520

    Chen A, Yolton K, Rauch S, Webster GM, Hornung R, Sjödin A, Dietrich KN, Lanphear BP. Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. children through 5 years of age: The HOME Study. Environmental Health Perspectives 2014;122(8):856-862

    Kato K, Wong LY, Chen A, Dunbar C, Webster GM, Lanphear BP, Calafat AM. Changes in serum concentrations of maternal poly- and perfluoroalkyl substances over the course of pregnancy and predictors of exposure in a multiethnic cohort of Cincinnati, Ohio pregnant women during 2003–2006. Environmental Science and Technology 2014 (Epub ahead of print, July 29)