News and Events page for the latest
in UC SBRP work!
is the University of Cincinnati SBRP?
In 1980, U.S. Congress passed the
Comprehensive Environmental Response,
and Liability Act, called CERCLA. This
act enabled the U.S. Environmental
Protection Agency (EPA) to respond to
hazardous spills, force companies to
clean up their waste, and establish a
system to clean up abandoned sites.
Industries that tended to be the biggest
polluters were taxed, and this money was
set up in a trust called the Superfund.
The money in this trust has been used to
clean up sites that pose the most
imminent and substantial threats to the
environment, and to human health.
It soon became clear that a better
understanding of pollution was needed in
order to clean up the contaminated
sites. This includes understanding which
materials are hazardous to environmental
and human health, and how to get rid of
the toxins on a site. In order to gain
this understanding, the Superfund Basic
Research Program was formed as part of
the Superfund Amendments and
Reauthorization Act (SARA) of 1986. The
goal of the SBRP is to establish
multidisciplinary programs at academic
institutions to address the various
health and environmental issues that
arise from the complex nature of
The University of Cincinnati SBRP is
focused on understanding the effects
that mixtures of different chemicals and
metals can have on human health.
Specific chemicals of interest to the
SBRP at UC include arsenic, chromium,
and polycyclic aromatic hydrocarbons,
called PAHs. Initially funded in 1988,
this program is currently under the
leadership of Paul L. Bishop, with
Alvaro Puga as the Deputy Director.
Current biomedical projects study the
mechanisms underlying the mutagenic
properties of arsenic, and how
co-exposure to other contaminants such
as PAHs can alter that mutagenic
potential. The engineering and
biological sciences projects focus on
the bioremediation of these mixtures.
The synergy of several departments
working together on related projects has
led to new insights in the health
effects and bioremediation of these
contaminants. Aided by the Analytical,
Biostatistics, Outreach, Research
Translation, and Training Cores, the UC
SBRP works to meet the aims of research,
education, and public service.
A summary of the UC SBRP was written up
in the Center for Environmental Genetics
Interface, Issue 27.
The UC Superfund Shorts is an
occasional newsletter produced by the
Administrative Core. This
publication provides the scientists,
associates, students, and other
interested parties with an easy way to
stay informed on the various projects
that make up this program.
The most recent issue is available here.
The first issue
is available here.